王云云

2012.9-2020.6

华中科技大学 生物化学与分子生物学

理学博士生

2015.11-2017.11

法国蒙彼利埃大学 神经生物学

联合培养博士生

2010.9- 2012.6

华中科技大学 生物化学与分子生物学

理学硕士生

2006.9-2010.6

信阳师范学院 生物科学

理学学士

（2）国家自然科学基金，91539107，利用微流控芯片技术研究AcSDKP对血管损伤后的重塑作用和机制，参与

（3）国家自然科学基金，31511130131，中枢神经系统重要神经递质γ-氨基丁酸的B型受体的神经信号转导机制研究，参与

（4）国家留学基金委，中法蔡元培交流合作项目，CSC NO. 201404490167 “苯胺基嘧啶类杀真菌剂对神经发育及神经退行性疾病的影响研究”

5.已发表论文

1. Pierre-André Lafon¹ ,*, Yunyun   Wang^1,2,*, Margarita Arango-Lievano³ , Joan Torrent¹, Lucie Savador-Prince¹,   Marine Mansuy¹ , Nadine Mestre-Francès¹ , Jianfeng Liu² , Josep Vicent Mercader⁵ , Freddy Jeanneteau³ , Catherine Desrumaux¹ & Véronique Perrier¹ . Fungicide residues exposure and   β-amyloid aggregation in a mouse model of Alzheimer’s disease. Environmental   Health Perspectives. doi:10.1289/EHP5550 (2020)（共一作）IF：8.4 (Highlighted by CNRS， the   journal called "Le Monde" )

2. Yunyun Wang¹ ,*, Chanjuan Xu¹ ,*, Wenhua Zhang^1,3, Xuetao Huang¹ ,   Shumin Ma¹, Yujia Huo¹ , Yichen Wu¹, Haijun Tu^1,4, Jianfeng Liu¹.   GABAB receptors couple to G13 to control specific neuronal function. Science   Signaling. 二审中(2020)

3. Yunyun Wang*, Pierre-André Lafon*, Elisabeth   Huetter, Nathalie Chevallier, Laurent Givalois, Catherine Desrumaux, Jianfeng   Liu, and Véronique Perrier. Prenatal   exposure to low doses of fungicides increases neurogenesis in neonates and   predisposes to the onset of Alzheimer’s disease! In submission. (2020)

4. Pierre--André Lafon*,   Thibaut Imberdis*, Yunyun Wang,   Joan Torrent, Mike Robitzer, Elisabeth Huetter, Maria-Teresa   Alvarez-Martinez, Nathalie Chevallier, Laurent Givalois, Catherine Desrumaux,   Jianfeng Liu, and Véronique Perrier. Low   doses of bioherbicide favours prion aggregation and propagation in vivo.   Sci. Rep. 2018, 8:8023. doi:10.1038/s41598-018- 25966-9.   (2018)

5. Véronique   Perrier¹‡, Thibaut Imberdis¹, Pierre-André Lafon¹,   Marina Cefis¹, Yunyun   Wang^1,2, Elisabeth Huetter¹, Jacques-Damien   Arnaud³, Teresa Alvarez-Martinez³, Naig Le Guern^{4,   5}, Guillaume Maquart^{4, 5}, Laurent Lagrost^{4, 5, 6},   Catherine Desrumaux^{1, 5}‡. Plasma cholesterol level determines   in vivo prion propagation. J Lipid Res. 2017   Oct;58(10):1950-1961. doi: 10.1194/jlr.M073718. (2017)

6. Wenhua   Zhang¹,*, Chanjuan Xu¹,*, Haijun Tu¹,*, Yunyun Wang¹, Qian   Sun¹, Ping Hu¹, Yongjian Hu¹, Philippe   Rondard²&Jianfeng Liu¹. GABAB receptor upregulates fragile X mental retardation protein   expression in neurons. Sci. Rep.5,10468; doi:10.1038/srep10468 (2015)

7. Zongyong   Zhang¹,*,Wenhua Zhang¹,*, Siluo Huang¹,*,‡,   Qian Sun¹, YunyunWang¹,   Yongjian Hu¹, Ninghua Sun¹,Yilei Zhang¹,   Zhihua Jiang¹, Nagahiro Minato², Jean-Philippe Pin³,Li   Su¹,‡ and Jianfeng Liu¹,‡. GABAB receptor promotes its own surface expression by recruiting a   Rap1-dependent signaling cascade. J Cell Sci. 128, 2302-2313   doi:10.1242/jcs. 167056(2015)

8. Guillaume   A. Baloucoune., Lei Chun., Wenhua Zhang., Chanjuan Xu, Siluo Huang, Qian Sun,   Yunyun Wang, Haijun Tu,   Jianfeng Liu*. GABAB Receptor Subunit   GB1 at the Cell Surface Independently Activates ERK1/2 through IGF-1R   Transactivation. PLoS ONE 7(6): e39698. doi:10.1371/journal.pone.0039698   (2012)

9. 张文华，王云云，丁明柳，刘剑峰. GABA受体与脆性X染色体综合征研究新进展.生物物理学报，2013; 29 (11).793-800