一、个人简介:
王梅娜,中共党员,博士,河南大学基础医学院校聘副教授,中国微循环学会转化医学专业委员会青年委员。
二、主要研究方向:
肿瘤发生和转移的分子机制,DNA损伤修复与肿瘤调控。
三、已发表论文:
1. Meina Wang, Kaili Long, Enjie Li, Lulu Li, Binghua Li, Shusheng Ci, Lingfeng He, Feiyan Pan, Zhigang Hu, Zhigang Guo, DNA polymerase beta modulates cancer progression via enhancing CDH13 expression by promoter demethylation, Oncogene, 2020, 39(33):5507-5519(IF 9.867,一区)
2. Meina Wang, Enjie Li, Lin Lin, Alagamuthu Karthick Kumar, Feiyan Pan, Lingfeng He, Jing Zhang, Zhigang Hu, and Zhigang Guo, Enhanced activity of variant DNA polymerase β (D160G) contributes to cis platin therapy by impeding the efficiency of NER; Molecular Cancer Research; 2019, 17(10): 2077-2088(IF 5.852,二区)
3. Meina Wang, Lulu Li, Rui Liu, Yuwei Song, Xinxin Zhang, Weijing Niu, Alagamuthu Karthick Kumar, Zhigang Guo, Zhigang Hu, Obesity-induced overexpression of miRNA-24 regulates cholesterol uptake and lipid metabolism by targeting SR-B1; Gene; 2018, 668, 196-203(IF 3.688,三区)
4. Rui Liu, Meina Wang, Enjie Li, Yang Yang, Jiaxin Li, Siyu Chen, Wen-Jun Shenc, Salman Azharc, Zhigang Guo, Zhigang Hu,Dysregulation of microRNA-125a contributes to obesity-associated insulin resistance and dysregulates lipid metabolism in mice,BBA - Molecular and Cell Biology of Lipids,Biochim Biophys Acta Mol Cell Biol Lipids. 2020 1865(5):158640(IF 4.698,二区)
5. Xiao Lu, Rui Liu, Meina Wang, Alagamuthu Karthick Kumar1, Feiyan Pan1, Lingfeng He1, Zhigang Hu, Zhigang Guo. MicroRNA-140 impedes DNA repair by targeting FEN1 and enhances chemotherapeutic response in breast cancer. Oncogene, 2020;39:234–47(IF 9.867,一区)
6. Xia Wen, Shusheng Ci, Menghan Li, Meina Wang, Grigory L. Dianov, Zhuang Ma, Lulu Li, Ke Hua, Karthick Kumar Alagamuthu, Lihong Qing, Libo Luo, Ashlin M. Edick, Lingjie Liu, Zhigang Hu, Lingfeng He, Feiyan Pan, Zhigang Guo. Two-way crosstalk between BER and c-NHEJ repair pathway is mediated by Pol β and Ku70; Faseb Journal; 2019, 33(11), 11668-11681(IF 5.191,二区)
四、讲授课程:系统解剖学
五、联系方式(邮箱):10190177@henu.edu.cn